Principal Scientist / Senior Scientist - Bioanalysis (m/f)

Opis posla

        The Bioanalytical team within DMPK plays a central role in evaluating test compounds by delivering quantitative and qualitative data for both in vitro and in vivo studies, along with physicochemical characterization across a range of modalities. The group develops and applies LC-MS/MS methods, performs complex sample analysis and interprets data to support scientific decision-making.  Continuous improvement is a core focus, including implementation of automation, advanced extraction techniques, and high-throughput LC-MS workflows.

Key  responsibilities:
- Lead the development, optimization, and implementation of LC-MS/MS bioanalytical methods for small molecules, peptides, biomarkers, and metabolites in complex biological matrices
- Drive innovation by evaluating and implementing new analytical technologies and methodologies to address challenging assay needs
- Oversee and actively contribute to laboratory activities, including sample preparation, data generation and instrument operation
- Provide technical leadership, mentoring and hands-on guidance to junior scientists within the team
- Troubleshoot complex analytical and instrumentation issues, ensuring robust and reliable assay performance
- Contribute to metabolite identification and structural elucidation in collaboration with DMPK and medicinal chemistry teams
- Assist in the preparation of study proposals, statements of work, and cost estimates, coordinate timelines and resources for project execution
- Identify opportunities to expand scientific capabilities and contribute to strategic development of bioanalytical services
- Pursue ongoing professional development by engaging in scientific training, presenting data, and staying current with advancements in the field

Uvjeti:
- Graduate degree (MSc or PhD) in Analytical Chemistry, Chemistry, Pharmacy, Biotechnology, or a related field
- Solid experience in LC-MS/MS based bioanalysis including method development and troubleshooting
- Strong understanding of sample preparation techniques and bioanalytical workflows
- Proven ability to work independently while contributing to team and project leadership
- Computing skills, including word processing and use of spreadsheets (e.g., Microsoft Office packages and Microsoft Project)

Benefiti:
- A key scientific role with influence on bioanalytical strategy and project outcomes
- Opportunities to lead and shape bioanalytical approaches within drug discovery programs
- Access to advanced analytical technologies and laboratory automation
- A collaborative, international environment with strong scientific exchange
- Ongoing training and professional development to support your career growth
    

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